Heart disease causes inflammation of the lining of the circulatory system. After a certain point that is poorly understood right now, the body begins to loose that battle and resorts to plan B. It uses small dense particles of cholesterol to shore up the inflamed weakened lining of the arteries. This is usually a slow process but it eventually closes some of those arteries. The inflammation itself causes other problems in other organs but none so insidious as in the arterial lining.
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